Issue 33, 2011

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

Abstract

A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.

Graphical abstract: Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

Supplementary files

Article information

Article type
Communication
Submitted
17 May 2011
Accepted
20 Jun 2011
First published
19 Jul 2011

Chem. Commun., 2011,47, 9513-9515

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

Y. Yan and Z. Wang, Chem. Commun., 2011, 47, 9513 DOI: 10.1039/C1CC12885J

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