Issue 30, 2011
From the journal:

Chemical Communications

Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N†

Xin Wang,‡a   Elena Matei,‡b   Lingquan Deng,‡c   Olof Ramström,*c   Angela M. Gronenborn*b  and  Mingdi Yan*a  

* Corresponding authors

a Department of Chemistry, Portland State University, P.O. Box 751, Portland, Oregon, USA
E-mail: yanm@pdx.edu
Fax: +1 5037259525
Tel: +1 5037255756

b Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, USA
E-mail: amg100@pitt.edu
Tel: +1 4126489959

c Department of Chemistry, KTH-Royal Institute of Technology, Teknikringen 30, S-10044 Stockholm, Sweden
E-mail: ramstrom@kth.se
Fax: +46 87912333
Tel: +46 87906915

Abstract

Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVNQ50C and CVNMutDB.

Graphical abstract: Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N

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Article information

DOI
https://doi.org/10.1039/C1CC12981C
Article type
Communication
Submitted
21 May 2011
Accepted
19 Jun 2011
First published
30 Jun 2011

Chem. Commun., 2011,47, 8620-8622

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Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N

X. Wang, E. Matei, L. Deng, O. Ramström, A. M. Gronenborn and M. Yan, Chem. Commun., 2011, 47, 8620 DOI: 10.1039/C1CC12981C

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