Issue 4, 2012

Direct N-alkylation of amino-azoles with alcohols catalyzed by an iridium complex/base system

Abstract

The direct and regioselective N-alkylation of amino-azoles to the corresponding 2-N-(alkylamino)azoles using various alcohols as alkylating agents with good to excellent yields has been accomplished by an iridium complex/base system.

Graphical abstract: Direct N-alkylation of amino-azoles with alcohols catalyzed by an iridium complex/base system

Supplementary files

Additions and corrections

Article information

Article type
Communication
Submitted
06 Aug 2011
Accepted
10 Nov 2011
First published
10 Nov 2011

Chem. Commun., 2012,48, 603-605

Direct N-alkylation of amino-azoles with alcohols catalyzed by an iridium complex/base system

F. Li, H. Shan, L. Chen, Q. Kang and P. Zou, Chem. Commun., 2012, 48, 603 DOI: 10.1039/C1CC14861C

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