Issue 48, 2011

Synthesis of isoindolinones viapalladium-catalyzed C–H activation of N-methoxybenzamides

Abstract

The synthesis of isoindolinones from N-methoxybenzamides and alkenes has been achieved by Pd-catalyzed ortho sp2 C–H activation and intramolecular oxidative amidation, which involve the cleavage of four bonds and formation of two bonds.

Graphical abstract: Synthesis of isoindolinones viapalladium-catalyzed C–H activation of N-methoxybenzamides

Supplementary files

Additions and corrections

Article information

Article type
Communication
Submitted
22 Sep 2011
Accepted
20 Oct 2011
First published
03 Nov 2011

Chem. Commun., 2011,47, 12789-12791

Synthesis of isoindolinones viapalladium-catalyzed C–H activation of N-methoxybenzamides

D. Li, T. Yuan and G. Wang, Chem. Commun., 2011, 47, 12789 DOI: 10.1039/C1CC15897J

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