Nucleic acid        amphiphiles: synthesis and self-assembled nanostructures

Minseok Kwak; Andreas Herrmann

doi:10.1039/C1CS15138J

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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures†

Minseok Kwak^a and Andreas Herrmann*^a

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* Corresponding authors

^a Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
E-mail: a.herrmann@rug.nl
Fax: +31 50 363 4400
Tel: +31 50 363 6318

Abstract

This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

This article is part of the themed collection: Advances in DNA-based nanotechnology

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Article information

DOI: https://doi.org/10.1039/C1CS15138J
Article type: Tutorial Review
Submitted: 24 May 2011
First published: 22 Aug 2011

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Chem. Soc. Rev., 2011,40, 5745-5755

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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

M. Kwak and A. Herrmann, Chem. Soc. Rev., 2011, 40, 5745 DOI: 10.1039/C1CS15138J

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