Issue 2, 2012

The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

Abstract

Oligosaccharide-modified poly(propylene imine) dendrimers are promising candidates as drug carriers and as anti-prion agents. Here, we report the biodistribution of maltotriose-modified 4th generation poly(propylene imine) (PPI) dendrimers and their ability to cross the blood–brain–barrier that is important if these glycodendrimers are considered as potential therapeutic agents in the central nervous system (CNS).

Graphical abstract: The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

Article information

Article type
Letter
Submitted
26 May 2011
Accepted
01 Aug 2011
First published
22 Aug 2011

New J. Chem., 2012,36, 350-353

The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

A. Janaszewska, B. Ziemba, K. Ciepluch, D. Appelhans, B. Voit, B. Klajnert and M. Bryszewska, New J. Chem., 2012, 36, 350 DOI: 10.1039/C1NJ20444K

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