Issue 8, 2011

The phytoalexins from cultivated and wild crucifers: Chemistry and biology

Abstract

Covering: 1986 to January 2011

Phytoalexins are antimicrobial secondary metabolites produced de novo by plants in response to stress, including microbial attack. In general, phytoalexins are important components of plant defenses against fungal and bacterial pathogens. The phytoalexins of crucifers are indole alkaloids derived from (S)-tryptophan, most of which contain a sulfur atom derived from cysteine. Beside their antimicrobial activity against different plant pathogenic species, cruciferous phytoalexins have shown anticarcinogenic effects on various human cell lines. This review focuses on the phytoalexins produced by cruciferous plants reported to date, with particular emphasis on their chemical synthesis, biosynthesis, metabolism by plant fungal pathogens and biological activities. A summary table containing all phytoalexins, their cultivated and wild cruciferous sources, their synthetic starting materials, biotransformation products and biological activities is provided.

Graphical abstract: The phytoalexins from cultivated and wild crucifers: Chemistry and biology

Article information

Article type
Review Article
Submitted
02 Mar 2011
Accepted
12 May 2011
First published
17 Jun 2011

Nat. Prod. Rep., 2011,28, 1381-1405

The phytoalexins from cultivated and wild crucifers: Chemistry and biology

M. S. C. Pedras, E. E. Yaya and E. Glawischnig, Nat. Prod. Rep., 2011, 28, 1381 DOI: 10.1039/C1NP00020A

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