Issue 14, 2011

Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines

Abstract

Stereoselective synthesis of 2,3-di- and 2,2′,3-tri-substituted aziridines in good yields and excellent diastereoselectivities are achieved through aza-Darzens reactions of a range of tert-butanesulfinyl aldimines and ketimines with ethyl bromoacetate.

Graphical abstract: Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines

Supplementary files

Article information

Article type
Communication
Submitted
08 Apr 2011
Accepted
17 May 2011
First published
18 May 2011

Org. Biomol. Chem., 2011,9, 5034-5035

Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines

T. M. Solá, I. Churcher, W. Lewis and R. A. Stockman, Org. Biomol. Chem., 2011, 9, 5034 DOI: 10.1039/C1OB05561E

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