Issue 21, 2011
From the journal:

Organic & Biomolecular Chemistry

One-pot synthesis of pyrrolo[1,2-a]quinoxalines†

Aiping Huang,a   Feng Liu,a   Chunjing Zhan,a   Yanli Liua  and  Chen Ma*ab  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shandong University, Jinan, P R China
E-mail: chenma@sdu.edu.cn

b State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, P R China

Abstract

A transition metal-free process for the regioselective synthesis of pyrrolo[1,2-a]quinoxalines under mild conditions in one-pot is described. The reaction afforded a variety of products in good to excellent yields. Indolo[1,2-a]quinoxalines were also synthesized from indole-2-carboxamides under the same conditions.

Graphical abstract: One-pot synthesis of pyrrolo[1,2-a]quinoxalines

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Article information

DOI
https://doi.org/10.1039/C1OB05936J
Article type
Paper
Submitted
10 Jun 2011
Accepted
04 Aug 2011
First published
05 Aug 2011

Org. Biomol. Chem., 2011,9, 7351-7357

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One-pot synthesis of pyrrolo[1,2-a]quinoxalines

A. Huang, F. Liu, C. Zhan, Y. Liu and C. Ma, Org. Biomol. Chem., 2011, 9, 7351 DOI: 10.1039/C1OB05936J

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