Issue 15, 2012

A new fluorescent and colorimetric probe for Cu2+ in live cells

Abstract

Based on a change in structure between spirocyclic (non-fluorescent) and ring-open (fluorescent) forms of rhodamine-based dyes, a new fluorescent and colorimetric Cu2+ probe was designed and synthesized. Upon treatment with Cu2+, the weakly fluorescent probe exhibited a strong fluorescence response with high selectivity. In addition, the turn-on fluorescent probe upon the addition of Cu2+ was applied in live cell imaging.

Graphical abstract: A new fluorescent and colorimetric probe for Cu2+ in live cells

Supplementary files

Article information

Article type
Paper
Submitted
28 Apr 2012
Accepted
18 May 2012
First published
18 May 2012

Analyst, 2012,137, 3466-3469

A new fluorescent and colorimetric probe for Cu2+ in live cells

W. Liu, H. Li, B. Zhao and J. Miao, Analyst, 2012, 137, 3466 DOI: 10.1039/C2AN35559K

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