Issue 12, 2012

A polycation-chaperoned in-stem molecular beacon system

Abstract

In the presence of poly(L-lysine)-graft-dextran, an in-stem molecular beacon involving three peryleneanthraquinone pairs in the stem region had a signal/background ratio of as high as 570. Response speed was also remarkable; equilibrium was attained within 5 minutes after addition of substrate DNA at 20 °C.

Graphical abstract: A polycation-chaperoned in-stem molecular beacon system

Supplementary files

Article information

Article type
Communication
Submitted
03 Nov 2011
Accepted
12 Dec 2011
First published
14 Dec 2011

Chem. Commun., 2012,48, 1760-1762

A polycation-chaperoned in-stem molecular beacon system

H. Asanuma, T. Osawa, H. Kashida, T. Fujii, X. Liang, K. Niwa, Y. Yoshida, N. Shimada and A. Maruyama, Chem. Commun., 2012, 48, 1760 DOI: 10.1039/C2CC16812J

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