Issue 19, 2012
From the journal:

Chemical Communications

A strong two-photon induced phosphorescent Golgi-specific in vitro marker based on a heteroleptic iridium complex†

C.-L. Ho,*ab   K.-L. Wong,a   H.-K. Kong,c   Y.-M. Ho,c   C. T.-L. Chan,d   W.-M. Kwok,d   K. S.-Y. Leung,a   H.-L. Tam,e   M. H.-W. Lam,c   X.-F. Ren,f   A.-M. Ren,f   J.-K. Fengf  and  W.-Y. Wong*ag  

* Corresponding authors

a Department of Chemistry and Institute of Advanced Materials, Hong Kong Baptist University, Kowloon Tong, Hong Kong, P. R. China
E-mail: rwywong@hkbu.edu.hk
Fax: +852 3411 7348
Tel: +852 3411 7074

b Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China

c Department of Biology and Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong, P. R. China

d Department of Applied Biology and Chemistry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P. R. China

e Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, P. R. China

f State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130023, P. R. China

g Institute of Molecular Functional Materials (Areas of Excellence Scheme), University Grants Committee, Hong Kong, P. R. China

Abstract

A new heteroleptic iridium complex demonstrated low cytotoxicity and near-infrared excitation (via two-photon absorption) for target-specific in vitro Golgi imaging in various cell lines (HeLa and A549 cells) with two-photon absorption cross section (∼350 GM) in DMSO.

Graphical abstract: A strong two-photon induced phosphorescent Golgi-specific in vitro marker based on a heteroleptic iridium complex

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Article information

DOI
https://doi.org/10.1039/C2CC16993B
Article type
Communication
Submitted
11 Nov 2011
Accepted
03 Jan 2012
First published
05 Jan 2012

Chem. Commun., 2012,48, 2525-2527

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A strong two-photon induced phosphorescent Golgi-specific in vitro marker based on a heteroleptic iridium complex

C.-L. Ho, K.-L. Wong, H.-K. Kong, Y.-M. Ho, C. T.-L. Chan, W.-M. Kwok, K. S.-Y. Leung, H.-L. Tam, M. H.-W. Lam, X.-F. Ren, A.-M. Ren, J.-K. Feng and W.-Y. Wong, Chem. Commun., 2012, 48, 2525 DOI: 10.1039/C2CC16993B

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