Issue 21, 2012
From the journal:

Chemical Communications

A general and selective copper-catalyzed reduction of secondary amides†

Shoubhik Das,a   Benoît Join,a   Kathrin Jungea  and  Matthias Beller*a  

* Corresponding authors

a Leibniz-Institut fur Katalyse e. V., A.-Einstein-Str. 29a, Rostock, Germany
E-mail: Matthias.Beller@catalysis.de
Fax: +49 (381)1281 51113
Tel: +49 (381)1281 113

Abstract

In situ-generated cationic copper/pybox catalyst systems allow for the selective reduction of secondary amides into the corresponding amines under mild conditions. This novel protocol has a wide substrate scope and shows good functional group tolerance.

Graphical abstract: A general and selective copper-catalyzed reduction of secondary amides

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Article information

DOI
https://doi.org/10.1039/C2CC17209G
Article type
Communication
Submitted
19 Nov 2011
Accepted
19 Jan 2012
First published
19 Jan 2012

Chem. Commun., 2012,48, 2683-2685

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A general and selective copper-catalyzed reduction of secondary amides

S. Das, B. Join, K. Junge and M. Beller, Chem. Commun., 2012, 48, 2683 DOI: 10.1039/C2CC17209G

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