Issue 23, 2012
From the journal:

Chemical Communications

Gold nanoparticle based signal enhancement liquid crystal biosensors for DNA hybridization assays†

Shengyuan Yang,ab   Yanmei Liu,a   Hui Tan,a   Chao Wu,a   Zhaoyang Wu,*a   Guoli Shena  and  Ruqin Yua  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
E-mail: zywu@hnu.edu.cn
Fax: +86-731-88821989
Tel: +86-731-88821989

b College of Public Health, University of South China, Hengyang 421001, China

Abstract

A novel signal enhanced liquid crystal biosensor based on using AuNPs for highly sensitive DNA detection has been developed. This biosensor not only significantly decreases the detection limit, but also offers a simple detection process and shows a good selectivity to distinguish perfectly matched target DNA from two-base mismatched DNA.

Graphical abstract: Gold nanoparticle based signal enhancement liquid crystal biosensors for DNA hybridization assays

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Article information

DOI
https://doi.org/10.1039/C2CC17861C
Article type
Communication
Submitted
16 Dec 2011
Accepted
17 Jan 2012
First published
18 Jan 2012

Chem. Commun., 2012,48, 2861-2863

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Gold nanoparticle based signal enhancement liquid crystal biosensors for DNA hybridization assays

S. Yang, Y. Liu, H. Tan, C. Wu, Z. Wu, G. Shen and R. Yu, Chem. Commun., 2012, 48, 2861 DOI: 10.1039/C2CC17861C

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