Issue 25, 2012

Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly

Abstract

A simple, highly sensitive and enzyme-free DNAzyme sensor based on target-catalyzed hairpin assembly is developed, which permits detection of 0.1 pM target DNA. Furthermore, this DNAzyme sensor is capable of detecting target DNA in real samples because of its high selectivity.

Graphical abstract: Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly

Supplementary files

Article information

Article type
Communication
Submitted
14 Jan 2012
Accepted
07 Feb 2012
First published
09 Feb 2012

Chem. Commun., 2012,48, 3112-3114

Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly

A. Zheng, J. Li, J. Wang, X. Song, G. Chen and H. Yang, Chem. Commun., 2012, 48, 3112 DOI: 10.1039/C2CC30305A

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