Issue 29, 2012
From the journal:

Chemical Communications

Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as ‘dispersible electrodes’†

Kyloon Chuah,a   Leo M. H. Lai,a   Ian Y. Goon,b   Stephen G. Parker,a   Rose Amalb  and  J. Justin Gooding*a  

* Corresponding authors

a School of Chemistry and The Australian Centre for Nanomedicine, University of New South Wales, Sydney, Australia
E-mail: justin.gooding@unsw.edu.au
Fax: +61 2 9385 6141
Tel: +61 2 9385 5384

b ARC Centre of Excellence for Functional Nanomaterials, School of Chemical Engineering, University of New South Wales, Sydney, Australia

Abstract

Herein, we demonstrate the use of modified gold-coated magnetic nanoparticles as ‘dispersible electrodes’ which act as selective capture vehicles for electrochemical detection of prostate-specific antigen (PSA). A key advantage of this system is the ability to quantify non-electrochemical active analytes such as proteins with unprecedented detection limits and fast response times.

Graphical abstract: Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as ‘dispersible electrodes’

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Article information

DOI
https://doi.org/10.1039/C2CC30512G
Article type
Communication
Submitted
23 Jan 2012
Accepted
17 Feb 2012
First published
17 Feb 2012

Chem. Commun., 2012,48, 3503-3505

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Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as ‘dispersible electrodes’

K. Chuah, L. M. H. Lai, I. Y. Goon, S. G. Parker, R. Amal and J. Justin Gooding, Chem. Commun., 2012, 48, 3503 DOI: 10.1039/C2CC30512G

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