Issue 39, 2012
From the journal:

Chemical Communications

Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells†

Leticia A. Montoyaa  and  Michael D. Pluth*a  

* Corresponding authors

a Department of Chemistry, University of Oregon, 1253 University of Oregon, Eugene, USA
E-mail: pluth@uoregon.edu
Tel: 01 541 346 7477

Abstract

Hydrogen sulfide (H2S) is an important biological messenger but few biologically-compatible methods are available for its detection. Here we report two bright fluorescent probes that are selective for H2S over cysteine, glutathione and other reactive sulfur, nitrogen, and oxygen species. Both probes are demonstrated to detect H2S in live cells.

Graphical abstract: Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

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Article information

DOI
https://doi.org/10.1039/C2CC30730H
Article type
Communication
Submitted
01 Feb 2012
Accepted
16 Mar 2012
First published
20 Mar 2012

Chem. Commun., 2012,48, 4767-4769

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Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

L. A. Montoya and M. D. Pluth, Chem. Commun., 2012, 48, 4767 DOI: 10.1039/C2CC30730H

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