Issue 42, 2012
From the journal:

Chemical Communications

Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes†

Bing Zhou,‡a   Yaxi Yang‡a  and  Yuanchao Li*a  

* Corresponding authors

a Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Road Zu Chong Zhi, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China
E-mail: ycli@mail.shcnc.ac.cn

Abstract

A rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes via C–H bond activation is described. The reaction is highly atom-economic and provides easy access to a wide variety of 2-aroylindoles.

Graphical abstract: Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes

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Article information

DOI
https://doi.org/10.1039/C2CC31351K
Article type
Communication
Submitted
23 Feb 2012
Accepted
26 Mar 2012
First published
26 Mar 2012

Chem. Commun., 2012,48, 5163-5165

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Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes

B. Zhou, Y. Yang and Y. Li, Chem. Commun., 2012, 48, 5163 DOI: 10.1039/C2CC31351K

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