Multifunctional fluorescent-magnetic polyethyleneimine functionalized Fe3O4–mesoporous silica yolk–shell nanocapsules for siRNA delivery

Lingyu Zhang; Tingting Wang; Lu Li; Chungang Wang; Zhongmin Su; Jiang Li

doi:10.1039/C2CC33472K

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Multifunctional fluorescent-magnetic polyethyleneimine functionalized Fe₃O₄–mesoporous silica yolk–shell nanocapsules for siRNA delivery†

Lingyu Zhang,^a Tingting Wang,^b Lu Li,^a Chungang Wang,*^a Zhongmin Su^a and Jiang Li*^c

Author affiliations

* Corresponding authors

^a Faculty of Chemistry, Northeast Normal University, Changchun, 130024 Jilin, P. R. China
E-mail: wangcg925@nenu.edu.cn

^b School of Chemistry & Environmental Engineering, Changchun University of Science and Technology, Changchun, P. R. China

^c Dental Hospital, Jilin University, Changchun 130041, P. R. China
E-mail: lijiang69@yahoo.com.cn

Abstract

A facile, mild, environmentally friendly and reproducible strategy was used to fabricate the multifunctional fluorescent-magnetic polyethyleneimine functionalized Fe₃O₄–mesoporous silica yolk–shell nanocapsules for simultaneous fluorescent tracking and magnetically guided small interfering RNA delivery.

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Article information

DOI: https://doi.org/10.1039/C2CC33472K
Article type: Communication
Submitted: 14 May 2012
Accepted: 10 Jul 2012
First published: 12 Jul 2012

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Chem. Commun., 2012,48, 8706-8708

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Multifunctional fluorescent-magnetic polyethyleneimine functionalized Fe₃O₄–mesoporous silica yolk–shell nanocapsules for siRNA delivery

L. Zhang, T. Wang, L. Li, C. Wang, Z. Su and J. Li, Chem. Commun., 2012, 48, 8706 DOI: 10.1039/C2CC33472K

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Chemical Communications