Issue 78, 2012

Enantioselective aza-Henry reactions of cyclic α-carbonyl ketimines under bifunctional catalysis

Abstract

The aza-Henry reaction of nitroalkanes with the C[double bond, length as m-dash]N group of 2-aryl-3H-indol-3-ones catalyzed by thiourea-chincona derivatives takes place with good yield and high ee's.

Graphical abstract: Enantioselective aza-Henry reactions of cyclic α-carbonyl ketimines under bifunctional catalysis

Supplementary files

Article information

Article type
Communication
Submitted
06 Jun 2012
Accepted
07 Aug 2012
First published
08 Aug 2012

Chem. Commun., 2012,48, 9759-9761

Enantioselective aza-Henry reactions of cyclic α-carbonyl ketimines under bifunctional catalysis

A. Parra, R. Alfaro, L. Marzo, A. Moreno-Carrasco, J. L. García Ruano and J. Alemán, Chem. Commun., 2012, 48, 9759 DOI: 10.1039/C2CC34053D

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