Issue 69, 2012

A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility

Abstract

We report a fully covalent, dual-signalling electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in probe flexibility for simple and robust detection of target DNA.

Graphical abstract: A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility

Supplementary files

Article information

Article type
Communication
Submitted
16 Jun 2012
Accepted
12 Jul 2012
First published
12 Jul 2012

Chem. Commun., 2012,48, 8703-8705

A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility

W. Yang and R. Y. Lai, Chem. Commun., 2012, 48, 8703 DOI: 10.1039/C2CC34312F

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