Issue 87, 2012
From the journal:

Chemical Communications

Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection†

Yunqiu Tu,a   Ping Wu,*a   Hui Zhanga  and  Chenxin Cai*a  

* Corresponding authors

a Jiangsu Key Laboratory of New Power Batteries, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, P.R. China
E-mail: wuping@njnu.edu.cn, cxcai@njnu.edu.cn
Fax: +86 25 85891767
Tel: +86 25 85891780

Abstract

We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.

Graphical abstract: Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection

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Article information

DOI
https://doi.org/10.1039/C2CC35564G
Article type
Communication
Submitted
01 Aug 2012
Accepted
20 Aug 2012
First published
21 Aug 2012

Chem. Commun., 2012,48, 10718-10720

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Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection

Y. Tu, P. Wu, H. Zhang and C. Cai, Chem. Commun., 2012, 48, 10718 DOI: 10.1039/C2CC35564G

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