Issue 88, 2012
From the journal:

Chemical Communications

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells†

Zheng Xu,‡a   Lin Xu,‡a   Ji Zhou,a   Yufang Xu,a   Weiping Zhua  and  Xuhong Qian*a  

* Corresponding authors

a Shanghai Key Laboratory of Chemical Biology, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, East China University of Science and Technology, Shanghai, China
E-mail: xhqian@ecust.edu.cn
Fax: +86 21 6425 2603
Tel: +86 21 6425 3589

Abstract

A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.

Graphical abstract: A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC36141H
Article type
Communication
Submitted
16 Jul 2012
Accepted
14 Sep 2012
First published
14 Sep 2012

Chem. Commun., 2012,48, 10871-10873

Permissions

Request permissions

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

Z. Xu, L. Xu, J. Zhou, Y. Xu, W. Zhu and X. Qian, Chem. Commun., 2012, 48, 10871 DOI: 10.1039/C2CC36141H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements