CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)3(tpm)]+

G. Dördelmann; Thomas Meinhardt; Thomas Sowik; Anke Krueger; Ulrich Schatzschneider

doi:10.1039/C2CC36491C

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)₃(tpm)]⁺†

G. Dördelmann,^a Thomas Meinhardt,^b Thomas Sowik,^a Anke Krueger*^b and Ulrich Schatzschneider*^a

Author affiliations

* Corresponding authors

^a Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany
E-mail: ulrich.schatzschneider@uni-wuerzburg.de
Fax: +49 931 3184605
Tel: +49 931 3183636

^b Institut für Organische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany
E-mail: krueger@chemie.uni-wuerzburg.de
Fax: +49 931 3184606
Tel: +49 931 3185334

Abstract

The copper-catalyzed 1,3-dipolar azide–alkyne cycloaddition (CuAAC) was used for the first time to attach a biologically active carbon monoxide delivery agent to modified nanodiamond (ND) as a highly biocompatible carrier. The [Mn(CO)₃(tpm)]⁺ photoactivatable CO-releasing molecule (PhotoCORM) on the surface retained the carbon monoxide release properties of the parent compound as shown with the myoglobin assay.

Download options Please wait...

Supplementary files

Supplementary information PDF (142K)

Article information

DOI: https://doi.org/10.1039/C2CC36491C
Article type: Communication
Submitted: 05 Sep 2012
Accepted: 09 Oct 2012
First published: 09 Oct 2012

Download Citation

Chem. Commun., 2012,48, 11528-11530

Permissions

Request permissions

CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)₃(tpm)]⁺

G. Dördelmann, T. Meinhardt, T. Sowik, A. Krueger and U. Schatzschneider, Chem. Commun., 2012, 48, 11528 DOI: 10.1039/C2CC36491C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications