Issue 16, 2012
From the journal:

Dalton Transactions

Synthesis and characterization of novel chiral NHC–palladium complexes and their application in copper-free Sonogashira reactions†

Longguang Yang,a   Pei Guan,a   Pan He,a   Qian Chen,a   Changsheng Cao,*a   Yu Peng,b   Zhan Shi,b   Guangsheng Pangb  and  Yanhui Shi*ac  

* Corresponding authors

a School of Chemistry and Chemical Engineering and Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China
E-mail: yhshi_2000@126.com
Fax: +86-516-83500349
Tel: +86-516-83500349

b State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, Jilin 130012, PR China

c State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing, Jiangsu 210093, PR China

Abstract

A new series of chiral N-heterocyclic carbene (NHC) palladium complexes were synthesized from a relatively inexpensive amino acid, L-phenylalanine. All these compounds were fully characterized by 1H-NMR, 13C-NMR and elemental analysis. The X-ray molecular structures of two of the complexes were reported. The catalytic activity of the four palladium complexes was successfully tested in the Sonogashira reaction under copper free conditions in air. The palladium complex 3a provided good activity in the Sonogashira coupling reaction.

Graphical abstract: Synthesis and characterization of novel chiral NHC–palladium complexes and their application in copper-free Sonogashira reactions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2DT12391F
Article type
Paper
Submitted
12 Dec 2011
Accepted
12 Feb 2012
First published
13 Feb 2012

Dalton Trans., 2012,41, 5020-5025

Permissions

Request permissions

Synthesis and characterization of novel chiral NHC–palladium complexes and their application in copper-free Sonogashira reactions

L. Yang, P. Guan, P. He, Q. Chen, C. Cao, Y. Peng, Z. Shi, G. Pang and Y. Shi, Dalton Trans., 2012, 41, 5020 DOI: 10.1039/C2DT12391F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements