Issue 15, 2012

Facile synthesis of water-soluble, highly fluorescent graphenequantum dots as a robust biological label for stem cells

Abstract

We present a facile electrochemical method for synthesizing uniform sized graphene quantum dots (GQDs) with a strong yellow emission at 14% quantum yield. This approach has enabled a large-scale production of aqueous GQD solution without the need for polymeric or surfactant stabilizers. The structure and emission mechanism of the GQDs have been studied by combining extensive characterization techniques, rigorous control experiments and theoretical calculations. We further demonstrate the distinctive advantages of such GQDs for direct and efficient stem cell labeling, opening up great opportunities for their bio-medical applications.

Graphical abstract: Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells

Supplementary files

Article information

Article type
Paper
Submitted
25 Dec 2011
Accepted
15 Feb 2012
First published
09 Mar 2012

J. Mater. Chem., 2012,22, 7461-7467

Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells

M. Zhang, L. Bai, W. Shang, W. Xie, H. Ma, Y. Fu, D. Fang, H. Sun, L. Fan, M. Han, C. Liu and S. Yang, J. Mater. Chem., 2012, 22, 7461 DOI: 10.1039/C2JM16835A

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