Issue 9, 2012

Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets

Abstract

We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Each droplet in the array forms a stable environment of pico-litre volume to implement a single-cell-based assay.

Graphical abstract: Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets

Supplementary files

Article information

Article type
Communication
Submitted
19 Dec 2011
Accepted
23 Feb 2012
First published
28 Feb 2012

Lab Chip, 2012,12, 1594-1597

Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets

E. Um, E. Rha, S. Choi, S. Lee and J. Park, Lab Chip, 2012, 12, 1594 DOI: 10.1039/C2LC21266H

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