Issue 19, 2012

Amperometric biosensor based on 3D ordered freestanding porous Pt nanowire array electrode

Abstract

A three-dimensionally (3D) ordered freestanding porous platinum (Pt) nanowire array electrode (PPNWAE) with pores of several nanometers in size and a Pt nanowire array electrode (PNWAE) without pores were facilely fabricated by metal electrodeposition and direct integration with a Pt disk electrode. The unusual PPNWAE with high active area showed excellent sensitivity (0.36 mA cm−2 mM−1) and a wide detection range (4.5 μM–27.1 mM) to hydrogen peroxide (H2O2). A glucose oxidase (GOD)-based biosensor (PPNWAE/GOD) with a considerably wide detection range (4.5 μM–189.5 mM) to glucose was demonstrated. Furthermore, a lower detection limit, higher sensitivity and smaller value of Michaelis–Menten constant km were recorded for PPNWAE-based biosensors compared with PNWAE-based biosensors. Particularly, the response current to glucose of PPNWAE/GOD was ca. 100% higher than that of PNWAE/GOD and the response current to H2O2 of PPNWAE was ca. 50% higher than that of PNWAE, owing to the granular and rougher porous nanowire surface enabling greater bioactivity for GOD. The selectivity of PPNWAE/GOD glucose biosensor was also estimated.

Graphical abstract: Amperometric biosensor based on 3D ordered freestanding porous Pt nanowire array electrode

Supplementary files

Additions and corrections

Article information

Article type
Paper
Submitted
22 May 2012
Accepted
17 Jul 2012
First published
20 Jul 2012

Nanoscale, 2012,4, 6025-6031

Amperometric biosensor based on 3D ordered freestanding porous Pt nanowire array electrode

Y. Wang, Y. Zhu, J. Chen and Y. Zeng, Nanoscale, 2012, 4, 6025 DOI: 10.1039/C2NR31256E

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