Issue 4, 2013

Enzyme-mimetic effects of gold@platinum nanorods on the antioxidant activity of ascorbic acid

Abstract

Au@Pt nanorods were prepared by growing platinum nanodots on gold nanorods. Using electron spin resonance (ESR), we determined that the mechanisms for oxidation of ascorbic acid (AA) by Au@Pt nanorods and ascorbic acid oxidase (AAO) were kinetically similar and yielded similar products. In addition we observed that Au@Pt nanorods were stable with respect to temperature and pH. Using UV-VIS spectroscopy, the apparent kinetics of enzyme-mimetic activity of Au@Pt nanorods were studied and compared with the activity of AAO. With the help of ESR, we found that Au@Pt nanorods did not scavenge hydroxyl radicals but inhibited the antioxidant ability of AA for scavenging hydroxyl radicals produced by photoirradiating solutions containing titanium dioxide and zinc oxide. Moreover, the Au@Pt nanorods reduced the ability of AA to scavenge DPPH radicals and superoxide radicals. These results demonstrate that Au@Pt nanorods can reduce the antioxidant activity of AA. Therefore, it is necessary to consider the effects of using Pt nanoparticles together with other reducing agents or antioxidants such as AA due to the oxidase-like property of Au@Pt nanorods.

Graphical abstract: Enzyme-mimetic effects of gold@platinum nanorods on the antioxidant activity of ascorbic acid

Supplementary files

Article information

Article type
Paper
Submitted
08 Oct 2012
Accepted
10 Dec 2012
First published
13 Dec 2012

Nanoscale, 2013,5, 1583-1591

Enzyme-mimetic effects of gold@platinum nanorods on the antioxidant activity of ascorbic acid

Y. Zhou, W. He, W. G. Wamer, X. Hu, X. Wu, Y. M. Lo and J. Yin, Nanoscale, 2013, 5, 1583 DOI: 10.1039/C2NR33072E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements