Issue 47, 2012

A highly active catalytic system for Suzuki–Miyaura cross-coupling reactions of aryl and heteroaryl chlorides in water

Abstract

An easily available Pd(OAc)2/(2-mesitylindenyl)dicyclohexylphosphine/Me(octyl)3N+Cl/K3PO4·3H2O catalytic system was developed and it shows high catalytic activity in the Suzuki–Miyaura cross-coupling reaction of a diverse array of aryl and heteroaryl chlorides in water. Notably, this catalytic system also works with ultra-low loading of the catalyst with high turnover numbers.

Graphical abstract: A highly active catalytic system for Suzuki–Miyaura cross-coupling reactions of aryl and heteroaryl chlorides in water

Supplementary files

Article information

Article type
Paper
Submitted
26 Jul 2012
Accepted
17 Oct 2012
First published
17 Oct 2012

Org. Biomol. Chem., 2012,10, 9410-9417

A highly active catalytic system for Suzuki–Miyaura cross-coupling reactions of aryl and heteroaryl chlorides in water

S. Mao, Y. Sun, G. Yu, C. Zhao, Z. Han, J. Yuan, X. Zhu, Q. Yang and S. Liu, Org. Biomol. Chem., 2012, 10, 9410 DOI: 10.1039/C2OB26463C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements