A key intermediate for the total synthesis of lycorine has been prepared in racemic form; the optically pure form of this epoxylycorinane lactam, obtained from lycorine, has been reconverted into the alkaloid.
Y. Tsuda, T. Sano, J. Taga, K. Isobe, J. Toda, H. Irie, H. Tanaka, S. Takagi, M. Yamaki and M. Murata, J. Chem. Soc., Chem. Commun., 1975, 933 DOI: 10.1039/C39750000933
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