Issue 22, 1979

(E,E)-10-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxoisobenzofuran-5-yl)4,8-dimethyldeca-4,8-dienoic acid: total synthesis and role in mycophenolic acid biosynthesis

Abstract

The title compound (2), a prenylogue of mycophenolic acid (4), has been synthesized by two different routes; experiments show unambiguously that (2) is a biosynthetic intermediate of mycophenolic acid.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1979, 1021-1022

(E,E)-10-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxoisobenzofuran-5-yl)4,8-dimethyldeca-4,8-dienoic acid: total synthesis and role in mycophenolic acid biosynthesis

L. Colombo, C. Gennari, D. Potenza, C. Scolastico and F. Aragozzini, J. Chem. Soc., Chem. Commun., 1979, 1021 DOI: 10.1039/C39790001021

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