Issue 12, 1981

Transition metal-catalysed N-alkylation of amines by alcohols

Abstract

Primary and secondary alcohols effect alkylation of primary and secondary amines in the presence of rhodium, iridium, and ruthenium compounds at ⩽ 100 °C, whereby selective monoalkylation of primary amines can be achieved and heterocyclic rings can be constructed by both inter- and intra-molecular processes.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1981, 611-612

Transition metal-catalysed N-alkylation of amines by alcohols

R. Grigg, T. R. B. Mitchell, S. Sutthivaiyakit and N. Tongpenyai, J. Chem. Soc., Chem. Commun., 1981, 611 DOI: 10.1039/C39810000611

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