Issue 6, 1982

Dimethyl sulphoxide as leaving group: applications in transition metal chemotherapy

Abstract

Sulphur-bound dimethyl sulphoxide (DMSO) hydrolyses slowly in complexes of platinum; incorporation of DMSO into molecular species such as [Pt(diamine)(DMSO)2]2+ results in water-soluble, less toxic derivatives with equivalent chemotherapeutic activity of those of the parent chloro-complexes.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1982, 331-332

Dimethyl sulphoxide as leaving group: applications in transition metal chemotherapy

N. Farrell, J. Chem. Soc., Chem. Commun., 1982, 331 DOI: 10.1039/C39820000331

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements