Issue 8, 1982

Biosynthesis of vitamin B12: isolation of 15,23-dihydrosirohydrochlorin, a biosynthetic intermediate: structural studies and incorporation experiments

Abstract

An enzyme system from the vitamin B12 producer Propionibacterium shermanii converts uro'gen-III(2) into 15,23-dihydrosirohydrochlorin (7), the structure being established by 1H and 13C n.m.r. spectroscopy; this dihydro-macrocycle is enzymically converted into cobyrinic acid (6).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1982, 455-457

Biosynthesis of vitamin B12: isolation of 15,23-dihydrosirohydrochlorin, a biosynthetic intermediate: structural studies and incorporation experiments

A. R. Battersby, K. Frobel, F. Hammerschmidt and C. Jones, J. Chem. Soc., Chem. Commun., 1982, 455 DOI: 10.1039/C39820000455

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements