SCHEDULED MAINTENANCE
The reaction of KHF2 with 1,2-anhydro-3,4- : 5,6-di-O-isopropylidene-1-C-nitro-D-mannitol (4) provides a rapid, stereospecific route to 2-deoxy-2-fluoro-D-glucose (2), the 18F-labelled analogue of which, (1), is an important radiopharmaceutical of use in medical imaging.
W. A. Szarek, G. W. Hay and M. M. Perlmutter, J. Chem. Soc., Chem. Commun., 1982, 1253 DOI: 10.1039/C39820001253
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