Biosynthesis of aflatoxins. Incorporation of [2-2H3]acetate into aflatoxin B1 by Aspergillus flavus
Abstract
The observation of an NIH shift on incorporation of [2H3]acetate into aflatoxin B1 in cultures of Aspergillus flavus provides evidence for the timing of deoxygenation and hydroxylation steps which are an essential part of the biosynthetic pathway.