Conversion of the N-benzylacetamido group into the acetamido group by autoxidation in potassium t-butoxide–dimethyl sulphoxide
Abstract
The N-benzylacetamido group is rapidly converted into the acetamido group at 20 °C by the action of molecular oxygen in a solution of potassium t-butoxide in sulphoxide and a general route to acetylated amines by the alkylation of N-bnzylacetamide and N-debenzylation by the above method is proposed.