Heptafluoro-p-tolyl and tetrafluoro-4-pyridyl as novel and selective protecting groups for phenolic and alcoholic functions: synthesis and cleavage of perfluoroaryl ethers of steroids

Abstract

The easily prepared heptafluoro-p tolyl and tetrafluoro-4-pyridyl ethers of a variety of steroids react with sodium methoxide in dimethylformamide to regenerate the parent steroid by a mechanism involving an aryl–oxygen cleavage.