Hydrocupration of alkynes: a simple synthesis of (E,E)-1,3-dienes
Abstract
Copper(I) hydride species, prepared in situ in tetrahydrofuran using NaBH4–MgBr2–Et3N–CuCl or NaH–MgBr2–CuCl reagent systems, convert terminal alkynes into (E,E)-1,3-dienes in good yields.