Issue 10, 1988

Catalytic asymmetric synthesis of highly functionalised compounds with six contiguous stereocentres

Abstract

Alcoholysis of the achiral epoxyanhydride (1) in the presence of a catalytic quantity of a cinchona alkaloid gives, in a single step, the chiral products (2) in up to 99% enantiomeric excess.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 632-634

Catalytic asymmetric synthesis of highly functionalised compounds with six contiguous stereocentres

R. A. Aitken, J. Gopal and J. A. Hirst, J. Chem. Soc., Chem. Commun., 1988, 632 DOI: 10.1039/C39880000632

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