Issue 23, 1989

Second generation tumour photosensitisers: the synthesis of octa-alkyl chlorins and bacteriochlorins with graded amphiphilic character

Abstract

Two series of polyhydroxy derivatives of hydroporphyrins are synthesised which have the hydroxy substituents at β-positions, or in a side chain: these amphiphilic systems are tested in vivo as tumour photosensitisers, and some are found to be very effective.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 1822-1823

Second generation tumour photosensitisers: the synthesis of octa-alkyl chlorins and bacteriochlorins with graded amphiphilic character

R. Bonnett, A. N. Nizhnik and M. C. Berenbaum, J. Chem. Soc., Chem. Commun., 1989, 1822 DOI: 10.1039/C39890001822

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