Issue 5, 1990

Approaches to the total synthesis of montanine-type alkaloids: a first synthesis of (±)-4a,11a-cis-11,11a-anti-5,11-methanomorphanthridine and its trans-isomer

Abstract

The title compounds (3) and (4) were synthesised by reductive cyclisation of cis- and trans-11-hydroxymethyl-N-tosylmorphanthridines (15) and (16) derived from cis- and trans-nitrocyclohexane derivatives (5) and (6) with sodium bis(2-methoxyethoxy)aluminium hydride in boiling toluene.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 420-421

Approaches to the total synthesis of montanine-type alkaloids: a first synthesis of (±)-4a,11a-cis-11,11a-anti-5,11-methanomorphanthridine and its trans-isomer

O. Hoshino, M. Ishizaki, K. Saito and K. Yumoto, J. Chem. Soc., Chem. Commun., 1990, 420 DOI: 10.1039/C39900000420

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