Issue 23, 1990

Synthesis of the staurosporine aglycone

Abstract

The staurosporine aglycone 3 has been synthesised in 22.6% overall yield from ethyl indole-2-acetate by a route which involves an intramolecular Diels–Alder reaction of the pyranoindolone 8 followed by nitrene mediated cyclisation.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 1667-1668

Synthesis of the staurosporine aglycone

C. J. Moody and K. F. Rahimtoola, J. Chem. Soc., Chem. Commun., 1990, 1667 DOI: 10.1039/C39900001667

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