Issue 11, 1991

Studies on the mechanism of deacetoxy–deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes

Abstract

Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the FeII/α-ketoglutarate dependent oxygenase, DAOC–DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is reported.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 768-770

Studies on the mechanism of deacetoxy–deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes

J. E. Baldwin, R. M. Adlington, N. P. Crouch, J. W. Keeping, S. W. Leppard, J. Pitlik, C. J. Schofield, W. J. Sobey and M. E. Wood, J. Chem. Soc., Chem. Commun., 1991, 768 DOI: 10.1039/C39910000768

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