Issue 22, 1994

A new reagent for the cleavage of fully protected peptides synthesised on 2-chlorotrityl chloride resin

Abstract

A mixture of hexafluoroisopropanol–dichloromethane (1:4 v/v) acts as a fast, effective and convenient reagent for cleaving protected peptide fragments with a minimal amount of racemization from 2-chlorotrityl chloride resin.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 2559-2560

A new reagent for the cleavage of fully protected peptides synthesised on 2-chlorotrityl chloride resin

R. Bollhagen, M. Schmiedberger, K. Barlos and E. Grell, J. Chem. Soc., Chem. Commun., 1994, 2559 DOI: 10.1039/C39940002559

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