Issue 1, 1995

Synthesis of a highly functionalised AB taxane ring system: formation of the eight-membered ring by an efficient 8-exo-tet alkylation of an α-sulfonyl anion

Abstract

An efficient, scalable route to a Taxol A ring synthon has been developed; its successful elaboration to a highly functionalized AB system by means of a novel nucleophilic ring closure is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 85-86

Synthesis of a highly functionalised AB taxane ring system: formation of the eight-membered ring by an efficient 8-exo-tet alkylation of an α-sulfonyl anion

D. Crich and S. Natarajan, J. Chem. Soc., Chem. Commun., 1995, 85 DOI: 10.1039/C39950000085

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