Issue 16, 2013
From the journal:

Analyst

Single molecule SERS and detection of biomolecules with a single gold nanoparticle on a mirror junction†

Li Li,ac   Tanya Hutter,b   Ullrich Steinerc  and  Sumeet Mahajan*ac  

* Corresponding authors

a Institute for Life Sciences, Highfield Campus, University of Southampton, UK
E-mail: S.Mahajan@soton.ac.uk

b Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK

c Department of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK

Abstract

Using the bianalyte method we unambiguously demonstrate that a single gold nanosphere on a metal film junction, in the so-called nanoparticle on a mirror configuration, is capable of single molecule detection with surface-enhanced Raman spectroscopy (SERS). Also this configuration serves as a convenient and highly sensitive SERS sensor for detection of biomolecules. Such simple nano-junction based systems are ideal for chemical and biomedical analysis.

Graphical abstract: Single molecule SERS and detection of biomolecules with a single gold nanoparticle on a mirror junction

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3AN00447C
Article type
Paper
Submitted
05 Mar 2013
Accepted
29 Apr 2013
First published
02 May 2013

Analyst, 2013,138, 4574-4578

Permissions

Request permissions

Single molecule SERS and detection of biomolecules with a single gold nanoparticle on a mirror junction

L. Li, T. Hutter, U. Steiner and S. Mahajan, Analyst, 2013, 138, 4574 DOI: 10.1039/C3AN00447C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements