Carbon dots and chitosan composite film based biosensor for the sensitive and selective determination of dopamine

Qitong Huang; Shirong Hu; Hanqiang Zhang; Jianhua Chen; Yasan He; Feiming Li; Wen Weng; Jiancong Ni; Xiuxiu Bao; Yi Lin

doi:10.1039/C3AN00510K

Carbon dots and chitosan composite film based biosensor for the sensitive and selective determination of dopamine

Qitong Huang,^a Shirong Hu,*^ab Hanqiang Zhang,^a Jianhua Chen,^ab Yasan He,^a Feiming Li,^a Wen Weng,^ab Jiancong Ni,^a Xiuxiu Bao^a and Yi Lin^a

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* Corresponding authors

^a Department of Chemistry and Environment Science, Zhangzhou Normal University, Zhangzhou 363000, PR China
E-mail: Hushirong6666@163.com
Fax: +86 596 2528075
Tel: +86 596 2528075

^b Fujian Province University Key Laboratory of Analytical Science, Zhangzhou Normal University, Zhangzhou 363000, PR China

Abstract

A simple, sensitive and reliable dopamine (DA) biosensor was developed based on a carbon dots (CDs) and chitosan (CS) composite film modified glassy carbon electrode (CDs–CS/GCE). Under optimal conditions, the CDs–CS/GCE showed a better electrochemical response for the detection of DA than that of the glassy carbon electrode (GCE). The oxidation peak current (I_pa) of DA was linear with the concentration of DA in the range from 0.1 μM to 30.0 μM with the limit of detection as 11.2 nM (3S/N). The CDs–CS/GCE was applied to the detection of DA content in an injection solution of DA with satisfactory results.

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Carbon dots and chitosan composite film based biosensor for the sensitive and selective determination of dopamine

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Carbon dots and chitosan composite film based biosensor for the sensitive and selective determination of dopamine

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