Issue 5, 2013
From the journal:

Analyst

Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry†

Ning Pan,‡ab   Pengyuan Liu,‡b   Weidong Cui,c   Bo Tang,a   Jingmin Shia  and  Hao Chen*b  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan, China

b Center for Intelligent Chemical Instrumentation, Department of Chemistry and Biochemistry, Ohio University, Athens, OH, USA 45701
E-mail: chenh2@ohio.edu
Fax: +1 740 597 3157
Tel: +1 740 593 0719

c Department of Chemistry, Washington University, St. Louis, MO, USA 63130

Abstract

A fast and novel strategy for efficient ionization of phosphopeptides in mixtures is reported, in which the sample is acidified to low pH to suppress the deprotonation of phosphate groups and then followed by direct analysis using liquid sample desorption electrospray ionization mass spectrometry (DESI-MS).

Graphical abstract: Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3AN36737A
Article type
Communication
Submitted
22 Nov 2012
Accepted
09 Jan 2013
First published
09 Jan 2013

Analyst, 2013,138, 1321-1324

Permissions

Request permissions

Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

N. Pan, P. Liu, W. Cui, B. Tang, J. Shi and H. Chen, Analyst, 2013, 138, 1321 DOI: 10.1039/C3AN36737A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements